Is 120μg Rh Immune Globulin sufficient for prophylactic treatment of postpartum Rh(D) negative women delivering an Rh(D) positive neonate?
نویسندگان
چکیده
منابع مشابه
Molecular analysis of Rh polypeptides in a family with RhD-positive and RhD-negative phenotypes.
To investigate the genetic basis of the Rh polypeptide gene, we attempted the isolation of cDNA clones for Rh polypeptide from a family with the RhD-positive and RhD-negative phenotypes using the reverse transcription (RT)-PCR method for each reticulocyte RNAs followed by subcloning. The isolated cDNAs showed the existence of another Rh-related clone (RhPII-1 cDNA, tentative designation) beside...
متن کامل[Guideline for prevention of RhD alloimmunization in RhD negative women].
Events following which anti-D immunoglobulin should be given to all RhD negative women with no anti-D antibodies: First trimester indications (50 microg)--termination of pregnancy, spontaneous abortion followed by instrumentation, ectopic pregnancy, chorionic villus sampling, partial molar pregnancy; Second and third trimester indications (100 microg)--amniocentesis, cordocentesis, other invasi...
متن کاملMolecular RHD screening of RhD negative donors can replace standard serological testing for RhD negative donors.
This work aims to assess the value of a generalized molecular RHD screening strategy which could replace routine serological screening of weak D by indirect antiglobulin test. Three independent studies were performed at the two Blood Transfusion Services Berne and Zurich. Donors investigated were 652 RhD negative, but RhC and/or RhE positive, 17,391 mainly Rhccee, and 8200 with normal RhCcEe ph...
متن کاملOccurrence of ABO And RhD Incompatibility with Rh Negative Mothers
INTRODUCTION Hemolytic disease of the newborn was first described in the medical literature 1609, when it was diagnosed in one French housewife. In 1932 Diamond and colleagues described the mutual relationship of fetal hydrops, jaundice, anemia and erythoblastosis, which was later called fetal erytroblastosis. Hemolytic disease of the newborn (HDN) in the strict sense is considered disease whos...
متن کاملMolecular cloning of RhD cDNA derived from a gene present in RhD-positive, but not RhD-negative individuals.
The Rh blood group system plays a major role in immune and nonimmune hemolytic states. Although an Rh cDNA has been previously cloned, there is no information on which Rh antigenic protein it encodes. Using polymerase chain reaction (PCR) amplification, we have identified this original Rh clone, here designated Rh21, and an additional Rh cDNA clone, Rh13, that is 96% nucleotide- and 92% amino a...
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ژورنال
عنوان ژورنال: Transfusion Medicine Reviews
سال: 2021
ISSN: 0887-7963
DOI: 10.1016/j.tmrv.2020.09.015